Noxa24® for Nitric Oxide Support:

The Innovative Core of Vascanox HP®

December 21, 2023

Learn About the Proprietary Blend in Calroy’s Next-Generation Nitric Oxide Solution

Vascanox HP® stands out in the field of nitric oxide supplementation with its proprietary blend, Noxa24®.

This unique formulation has been shown to support nitric oxide (NO) production, storage, and release in the body for up to 24 hours with a single dose.*†

†As measured by saliva NO test strips in an open label published study.

Why This Matters

The pivotal role of nitric oxide in vascular health was established in the 1990s with Nobel-prize winning research and has been substantiated by numerous subsequent studies.

Nitric oxide (NO) is a gaseous messenger molecule that plays a wide range of physiological roles, especially vasodilation: NO helps to relax and widen blood vessels, enabling healthy blood flow and normal blood pressure.

Multiple Pathways

NO is produced in the human body through several pathways, and Noxa24® in Vascanox HP® uniquely supports the most important of these:

  • Endogenous Pathway: NO is produced by the enzyme endothelial nitric oxide synthase (eNOS) when a signal is sent from the endothelial glycocalyx in response to the shear stress of flowing blood.
  • Dietary Pathway: Bacteria in the gut convert inorganic nitrate — consumed in foods such as leafy green vegetables — into nitrite. This is then converted to NO, which is rapidly defused throughout the body.
  • Hydrogen Sulfide (H2S) Synergy: H2S is another gaseous messenger molecule which supports nitric oxide storage and release, while playing its own role in vasodilation, endothelium protection, and cellular signaling.

Key Ingredients of Noxa24

The Noxa24 blend in Vascanox HP contains ingredients that support both the endogenous and dietary production of NO, and the synergistic expression of H2S.

  • Black Garlic Extract: Rich in S-allyl-L-cysteine (SAC), which supports the physiological production of both NO production and H2S.
  • Potassium Nitrate: A precursor for NO production.
  • Mixed Berry Extract: High in anthocyanins and polyphenols, this extract aids in enhancing eNOS expression and NO bioavailability.

The Noxa24 proprietary blend is produced under stringent quality control, adhering to current Good Manufacturing Practices (cGMPs). The ingredients are all on the GRAS (Generally Recognized As Safe) list, ensuring their safety.

The effectiveness of Vascanox HP can be quickly and easily assessed through salivary test strips, enabling clinicians to monitor its impact on NO levels.

Conclusion

Vascanox HP is a scientifically formulated product to support nitric oxide production and overall vascular health. The unique, proprietary Noxa24 blend at the heart of Vascanox HP targets multiple pathways for NO production.